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3

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T37861	Talabostat
	Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 and some other DASH family enzymes essentially as potently as it inhibits DPP-IV[1]. Talabostat stimulates the immune system by triggering a proinflammatory form of cell death in monocytes and macrophages known as pyroptosis. The inhibition of two serine proteases, DPP8 and DPP9,...
T13069	Talabostat isomer mesylate	Others	Others
	Talabostat isomer mesylate is an isomer of talabostat mesylate. Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available inhibitor of dipeptidyl peptidase IV (DPP-IV)(Ki of 0.18 nM).
T4042	Talabostat mesylate Val-boroPro,PT100	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Talabostat mesylate (PT100) 是一种具有口服活性和非选择性的二肽基肽酶 IV 抑制剂(IC50< 4 nM;Ki= 0.18 nM)。Talabostat mesylate 是成纤维细胞活化蛋白的第一个临床抑制剂(IC50= 560 nM)，抑制 DPP8/9 (IC50= 4/11 nM;Ki= 1.5/0.76 nM)，静息细胞脯氨酸二肽酶(IC50= 310 nM)、DPP2 和一些其他 DASH 家族酶。Talabostat mesylate 具有抗肿瘤和造血刺激活性。

化合物

Cat.No: T37861

Talabostat isomer mesylate

Cat.No: T13069

Target: Others

Talabostat mesylate

Cat.No: T4042

Synonym: Val-boroPro,PT100

Target: Proteasome, DPP-4

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02836	MFGE8 Protein, Human, Recombinant (His) SPAG10,HMFG,milk fat globule-EGF factor 8 protein,hP47,B...	Human	Baculovirus Insect Cells
	MFGE8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q08431-1.
TMPK-00850	MFGE8 Protein, Mouse, Recombinant (His) MFG-E8,Lactadherin,SPAG10,BA46,MFG1,SED1,E...	Mouse	HEK293 Cells
	MFGE8 (Milk Fat Globule EGF And Factor V/VIII Domain Containing) is a Protein Coding gene. Diseases associated with MFGE8 include Anal Paget's Disease and Topographical Agnosia. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Extracellular vesicle-mediated signaling in recipient cells. This protein plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing.
TMPY-05235	MFGE8 Protein, Human, Recombinant (His & Avi), Biotinylated HsT19888,SPAG10,MFGM,MFG-E8,OAcGD3S,milk fat globule-EGF fac...	Human	Baculovirus Insect Cells
	MFGE8 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 44.1 kDa and the accession number is Q08431.2.

重组蛋白

MFGE8 Protein, Human, Recombinant (His)

Cat.No: TMPY-02836

Species: Human

Expression System: Baculovirus Insect Cells

MFGE8 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00850

Species: Mouse

Expression System: HEK293 Cells

MFGE8 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05235

Species: Human

Expression System: Baculovirus Insect Cells

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